Clinical & Translational Research > Ocular Oncology > Professor Sarah Coupland

Professional Memberships 

• American Joint Committe on Cancer (Member)
• British Association for Ocular Pathology (Member)
• British Eye Study Group (BESG) (Member)
• British Lymphoma Pathology Group (Member)
• Deutsche Ophthalmologische Gesellschaft (Member)
• Deutschsprachige Ophthalmolopathologen (Member)
• EORTC Melanoma Group (Member)
• International Association of Pathology (Member)
• National Cancer Research Institute (Chair of Research Committee)
• Ocular Oncology Group (Member)
• British Association for Cancer Research (Member)
• European Association for Vision and Eye Research (Member)
• Royal College of Pathology (Member)

• Falkenhagen KM, Braziel RM, Coupland SE, Rosenbaum JT, Smith JR (2007) Malignant B cells from patients with primary central nervous system lymphoma express stromal cell-derived factor-1. American Journal of Clinical Pathology,127(4),pp.633-641 

• Falini B, Lenze D, Hasserjian R, Coupland S, Jaehne D, Soupir C, Liso A, Martelli MP, Bolli N, Bacci F, Pettirossi V, Santucci A, Martelli MF, Pileri S, Stein H (2007) Cytoplasmic mutated nucleophosmin (NPM) defines the molecular status of a significant fraction of myeloid sarcomas. Leukemia,(),pp.1566-70 

• Ghadjar P, Coupland SE, Na IK, Noutsias M, Letsch A, Stroux A, Bauer S, Buhr HJ, Thiel E, Scheibenbogen C, Keilholz U (2006) Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer. J Clin Oncol,24(12),pp.1910-1916 

• Appay V, Jandus C, Voelter V, Reynard S, Coupland SE, Rimoldi D, Lienard D, Guillaume P, Krieg AM, Cerottini JC, Romero P, Leyvraz S, Rufer N, Speiser DE (2006) New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site. J Immunol. ,177(3),pp.1670-8 

• Coupland SE, Hummel M, Stein H (2005) Molecular analysis of immunoglobulin genes in primary intraocular lymphoma. Invest Ophthalmol Vis Sci,46(10),pp.3507-3514 

• Coupland SE, Loddenkemper C, Charlotte F, Smith JR, Hummel M, Stein H (2005) Expression of immunoglobulin transcription factors in primary intraocular lymphoma and primary central nervous system lymphoma. Invest Ophthalmol Vis Sci,46(11),pp.3957-3964 

• Jahnke K, Coupland SE, Na IK , Loddenkemper C, Thiel E, Keilholz U, Scheibenbogen C (2005) Expression of the chemokine receptors CXCR4, CXCR5 and CCR7 in primary central nervous system lymphoma. Blood,106(1),pp.384-385 

• Coupland SE, Foss HD, Hidayat AA, Cockerham GC, Hummel M, Stein H (2002) Extranodal marginal zone B cell lymphomas of the uvea: an analysis of 13 cases. J Pathol,197(3),pp.333-40 

• Lake SL, Coupland SE, Taktak AFG, Damato BE. (2010) Whole-genome microarray detects deletions and loss of heterozygosity of chromosome 3 occurring exclusively in metastasizing uveal melanoma . Investigative Ophthalmology and Visual Science,51(10),pp.4884-91 

• Dopierala J, Lake SL, Coupland SE, Taktak AFG, Damato BE (2010) Genetic heterogeneity in uveal melanoma assessed by multiplex ligation-dependent probe amplification. Investigative Ophthalmology and Visual Science,51(10),pp.4898-905 

• Bradley KT, Arber DA, Brown MS, Chang CC, Coupland SE, de Baca ME, Ellis DW, Foucar K, Hsi ED, Jaffe ES, Lill M, McClure SP, Medeiros LJ, Perkins Sl, Hussong JW (2010) Protocol for the examination of specimens from patients with hematopoietic neoplasms of the ocular adnexa. Archives of Pathology and Laboratory Medicine,134(3),pp.336-340 

• Coupland SE (2010) A possible new role for helicobacter pylori in the development of ocular adnexal lymphoma. Invited Commentary. American Journal Hematology, In Press,(),pp. 

• Russo A, Coupland SE, Raja V, Damato BE (2010) Recurrent choroidal melanoma after brachytherapy in the eye with scleral calcification. Acta Ophthalmologica, Epub ahead of print,(),pp.
 
• Russo A, Coupland SE, O'Keefe M, Damato BE (2010) Choroidal melanoma in a 7-year-old child treated by trans-scleral local resection. Graefes Archive for Clinical and Experimental Ophthalmology ,248(5),pp.747-749 

• Coupland SE (2010) The challenge of the microenvironment in B-cell lymphomas. Histopathology, In Press,(),pp. 

• Damato BE, Dopierala J, Coupland SE (2010) Genotypic profiling of 452 choroidal melanomas with Multiplex Ligation-Dependent Probe Amplification. Clinical Cancer Research, In Press,(),pp. 

• Jmor F, Kalirai H, Taktak A, Damato B, Coupland SE (2010) HSP-27 protein expression in uveal melanoma: correlation with predicted survival. Acta Ophthalmologica, In Press,(),pp. 

• Damato B and Coupland SE (2009) Genomic typing of uveal melanoma. Arch Ophthalmol.,127(),pp.113-4 

• Damato B, Dopierala J, Klaasen A, van Dijk M, Sibbring J and Coupland SE (2009) Multiplex Ligation-Dependent Probe Amplification of uveal melanoma: correlation with metastatic death. Investigative Ophthalmology and Visual Science,50(7),pp.3048-55 

• Damato B and Coupland SE (2009) Translating uveal melanoma cytogenetics into clinical care. Arch Ophthalmol,127(4),pp.423-9 

• Coupland SE, Chan CC, Smith JR (2009) The pathophysiology of retinal lymphoma. Ocular Immunology and Inflammation,17(4),pp.227-37 

• Damato B and Coupland SE (2009) The management of conjunctival melanoma. Expert Rev Anticancer Ther,9(9),pp.1227-39 

• Finger PT; 7th Edition, AJCC-UICC Ophthalmic Oncology Task Force incl. Coupland SE (2009) The 7th edition AJCC staging system for eye cancer: an international language for ophthalmic oncology. Arch Pathol Lab Med,133(8),pp.1197-8 

• Coupland SE, Vorum H, Mandal N, Kalirai H, Honoré B, Urbak SF, Lake SL, Dopierala J and Damato BE (2009) Proteomics of uveal melanomas suggests HSP-27 as a possible surrogate marker of chromosome 3 loss. Investigative Ophthalmology and Visual Science,51(),pp.12-20  http://www.iovs.org/

• Angi M, Damato B, Kalirai H, Dodson A, Taktak A, Coupland SE (2009) Immunohistochemical assessment of mitotic count in uveal melanoma. Acta Ophthalmologica, Epub ahead of print,(),pp. 

• Coupland SE (2009) Self assessment: Lymph node pathology. Diagnostic Histopathology,15(12),pp.589-598 

• Damato B, Coupland SE (2009) A reappraisal of the significance of largest basal diameter of uveal melanoma. Eye,23(12),pp.2152-2160 

• Coupland SE, White VA, Rootman J, Damato B and Finger PT (2009) A TNM-based staging system for ocular adnexal lymphomas. Arch Path Lab Med,133(8),pp.1262-7 

• Damato B, Eleuteri A, Fisher AC, Coupland SE, Taktak AF (2008) Artificial Neural Networks Estimating Survival Probability after Treatment of Choroidal Melanoma. Ophthalmology,EPubmed(),pp. 

• Coupland SE (2008) The pathologist's perspective on vitreous opacities. Eye,(),pp. 

• Ghadjar P, Loddenkemper C, Coupland SE, Stroux A, Noutsias M, Thiel E, Christoph F, Miller K, Scheibenbogen C, Keilholz U. (2008) Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer. J Cancer Res Clin Oncol,134(11),pp.1181-1189 

• Ghadjar P, Loddenkemper C, Coupland SE, Stroux A, Noutsias M, Thiel E, Christoph F, Miller K, Scheibenbogen C, Keilholz U (2008) Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer. J Cancer Res Clin Oncol,134(11),pp.1181-9 

• Goldin-Lang P, Tran QV, Fichtner I, Eisenreich A, Antoniak S, Schulze K, Coupland SE, Poller W, Schultheiss HP, Rauch U (2008) Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis. Oncol Rep,20(1),pp.123-8 

• Na IK, Coupland SE, Adam C, Stroux A, Ghadjar P, Thiel E, Keilholz U, Scheibenbogen C (2008) Nuclear expression of CXCR4 in tumor cells of non small cell lung cancer is correlated with lymph node metastasis. Hum Pathol,39(12),pp.1751-5 

• Coupland SE and Damato B (2008) Molecular pathology of intraocular lymphomas. Expert Review of Ophthalmology,3(5),pp.543-551 

• Damato B and Coupland SE (2008) Conjunctival melanoma and melanosis: A reappraisal of terminology, classification and staging. Clin Experiment Ophthalmol,36(8),pp.786-95 

• Damato B and Coupland SE (2008) Managing patients with ocular melanoma: state of the art. Clin Experiment Ophthalmol,36(7),pp.589-9 

• Coupland SE and Damato B (2008) Understanding intraocular lymphomas. Clin Experiment Ophthalmol,36(6),pp.564-78 

• Damato B and Coupland SE (2008) Clinical mapping of conjunctival melanomas. British Journal of Ophthalmology,92(11),pp.1545-9 

• Na IK, Busse A, Scheibenbogen C, Ghadjar P, Coupland SE, Letsch A, Loddenkemper C, Stroux A, Bauer S, Thiel E, Keilholz U (2008) Identification of truncated chemokine receptor 7 (CCR7) in human colorectal cancer unable to localize to the cell surface and unreactive to external ligands. Int J Cancer,123(7),pp.1565-72 

• Coupland SE, Campbell I, Damato B (2008) Routes of extraocular extension of uveal melanoma: risk factors and influence on survival probability. Ophthalmology,115(10),pp.1778-85 

• Damato B and Coupland SE (2008) An audit of conjunctival melanoma treatment in Liverpool. Eye,23 (4),pp.801-9 

• Falkenhagen KM, Braziel RM, Coupland SE, Rosenbaum JT, Smith JR (2007) Malignant B cells from patients with primary central nervous system lymphoma express stromal cell-derived factor-1. American Journal of Clinical Pathology,127(4),pp.633-641 

• Coupland SE, Jaehne D, Hummel M, Stein H (2007) The tale and molecular trail of a disseminated ocular adnexal MALT lymphoma. Graefes Arch Clin Exp Ophthalmol. ,(),pp. 

• Schuler A, Coupland SE, Krause L, Bornfeld N (2007) Malignant and non-malignant uveitis-masquerade syndromes in childhood. Klin Monatsbl Augenheilkd,224(6),pp.477-82 

• Falini B, Lenze D, Hasserjian R, Coupland S, Jaehne D, Soupir C, Liso A, Martelli MP, Bolli N, Bacci F, Pettirossi V, Santucci A, Martelli MF, Pileri S, Stein H (2007) Cytoplasmic mutated nucleophosmin (NPM) defines the molecular status of a significant fraction of myeloid sarcomas. Leukemia,(),pp.1566-70 

• Damato BE, Duke C, Coupland SE, Hiscott P, Smith PA, Campbell I, Douglas A, Howard P (2007) Clinical cytogenetics in uveal melanoma: seven years experience. Ophthalmology,(),pp.