Clinical & Translational Research > Paediatric Cancer Biology > Professor Edwin Jesudason

External Examination Appointments  • University of Sheffield (MD) (2006)
• Cardiff University (Wales) (PhD) (2008)
• Karolinska Institute, University of Stockholm (PhD) (2009)

Editorial Roles  • Faculty of 1000 (Contributing member) (from 2009)
• Archives of Surgery (International Advisory Board Member) (from 2008)
• Developmental Biology (Peer reviewer) (from 2008)
• Theoretical Biology and Medical Modelling (Peer reviewer) (from 2007)
• British Medical Journal (Peer reviewer) (from 2007)
• Journal of The Royal Society of Medicine (Peer reviewer) (from 2006)
• Annals of Tropical Paediatrics (Peer reviewer) (from 2005)
• Croatian Medical Journal (Peer reviewer) (from 2005)
• Journal of Biological Chemistry (Peer reviewer) (from 2005)
• Journal of Paediatric Surgery (Peer reviewer) (from 2005)
• Archives of Disease in Childhood (Peer reviewer) (from 2004)
• Pediatric Surgery International (Peer reviewer) (from 2004)

External Roles  • Alder Hey Research Clinic, Alder Hey Children's Hospital NHS Foundation Trust (Founder member) (from 2007)
• Molecular Targeting Group, Paediatric Oncology, Alder Hey Children's Hospital NHS Foundation Trust (Member) (from 2004)
• Research Committee, British Association of Paediatric Surgeons (Member) (from 2006)
• Research Review Committee, Alder Hey Children's Hospital NHS Foundation Trust (Member) (from 2005)

Professional Memberships  • Medical Protection Society (Member)
• UK Children's Cancer Study Group (Member)
• UK Resuscitation Council Advanced Life Support Group (Member)
• British Association of Paediatric Surgeons (Member)
• Royal College of Surgeons of England (Fellow)

Personal Distinctions  • Invited Lecture, North West Development Agency (by North West Development Agency) (Mar 2009)
• Invited Lecture, UK Foreign Office and Saban Research Institute (by UK Foreign and Commonwealth Office) (occasion: Healthy Ageing Workshop) (Feb 2009)
• Invited Lecture, CCCRR Cambridge Respiratory Medicine Seminars (by CCCRR Cambridge Respiratory Medicine Seminars) (Sep 2008)
• Invited Lecture, Association of Laparoscopic Surgeons of Great Britain and Ireland (by Association of Laparoscopic Surgeons of Great Britain and Ireland) (occasion: Annual Congress) (2008)
• Health Foundation Leadership Fellowship (by The Health Foundation) (2005)
• BMJ International Working Party for The Campaign to Revitalise Academic Medicine (by British Medical Journal) (2004)
• Academy of Medical Sciences National Clinician Scientist (by Academy of Medical Sciences / The Health Foundation) (2002)
• Hunterian Professor (by Royal College of Surgeons of England) (2001)
• Indian Association of Paediatric Surgeons Keynote Lecture (by The Indian Association of Paediatric Surgeons 27th Annual Congress, Kerala, India) (2001)
• American Academy of Pediatrics Resident's Prize (by American Academy of Pediatrics 51 st Surgical Section Meeting) (1999)

Distinguished Visitors  • Professor David Warburton, Children's Hospital Los Angeles, in Jul 2007 - Invited lecture
• Professor Mark Walport, Director of The Wellcome Trust, in 2005 - The Inaugural UK National Clinician Scientist Meeting
• Dr Liam O'Toole, Chief Executive of The UK CRC, in 2005 - The Inaugural UK National Clinician Scientist Meeting
• Professor Robert Souhami, Cancer Research UK, in 2005 - The Inaugural UK National Clinician Scientist Meeting
• Professor Patrick Vallance, Academy of Medical Sciences, in 2005 - The Inaugural UK National Clinician Scientist Meeting
• Mrs Mary Manning, Chief Executive of The Academy of Medical Sciences, in 2005 - The Inaugural UK National Clinician Scientist Meeting

D Mullassery, ME Ba’ath, EC Jesudason, PD Losty (2010) The value of liver herniation in the prediction of outcome in fetal congenital diaphragmatic hernia - A systematic review and meta-analysis.. Ultrasound Obstet Gynecol vol 35 issue 5 pp 609-14

SM Thompson, EC Jesudason, JE Turnbull, DG Fernig (2010) Heparan sulfate in lung morphogenesis: The elephant in the room.. Birth Defects Res C Embryo Today vol 90 issue 1 pp 32-44

NK Lansdale, S Alam, PD Losty, EC Jesudason (2010) Neonatal Endosurgical Congenital Diaphragmatic Hernia (CDH) Repair: A Systematic Review and Meta-analysis. Ann Surg vol 252 issue 1 pp 20-6

SM Thompson, DG Fernig, EC Jesudason, PD Losty, EM van de Westerlo, TH van Kuppevelt, JE Turnbull (2009) Heparan sulphate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities. Journal of Biological Chemistry vol 284 issue 51 pp 35621-31

D Mullassery, EC Jesudason, C Dominici, HP McDowell, PD Losty (2009) Neuroblastoma - Contemporary Management. Arch Dis Child vol 94 issue 6 pp 177-85

H Carnaghan, EC Jesudason, D Miniati. (2009) Mechanical compression with secondary ischemia as a possible cause of atresias associated with omphalocele. J Pediatr Surg vol 44 issue 12 pp e9-e11

EC Jesudason (2009) Airway smooth muscle: an architect of the lung?. Thorax vol 64 issue 6 pp 541-5

Mullassery D, Llewellyn RS, Almond SL, Jesudason EC, Losty PD. (2008) Oesophageal atresia with cleft lip and palate: a marker for associated lethal anomalies?. Pediatr Surg Int vol 24 issue 7 pp 815-817

H Wallace, MG Connell, PD Losty, EC Jesudason, KS Southern. (2008) Embryonic lung growth is normal in a cftr-knockout mouse model.. Exp Lung Res vol 34 pp 717-27

Sinha AK, Jesudason EC, Mallucci CL, Losty PD, Kokai G, Pizer BL. (2008) Infantile myofibromatosis of the craniovertebral junction.. Br J Neurosurg vol 24 pp 1-3

Mullassery D, Perry D, Goyal A, Jesudason EC, Losty PD. (2008) Surgical practice for infantile hypertrophic pyloric stenosis in the United Kingdom and Ireland--a survey of members of the British Association of Paediatric Surgeons.. J Pediatr Surg vol 43 issue 6 pp 1227-9

Jesudason EC (2007) Exploiting mechanical stimuli to rescue growth of the hypoplastic lung. Pediatric Surgery International

Thompson SM, Connell MG, Fernig DG, Ten Dam GB, van Kuppevelt TH, Turnbull JE, Jesudason EC, Losty PD (2007) Novel 'phage display antibodies identify distinct heparan sulfate domains in developing mammalian lung. Pediatric Surgery International vol 23 issue 5 pp 411-417

Armstrong R, Fryer A, Pisipati S, Jesudason E. (2007) Evaluating the association between congenital cystic adenomatoid malformation of the lung and abdominal wall laxity.. Clinical Dysmorphology vol 16 issue 2 pp 77-80

Ba'ath ME, Jesudason EC, Losty PD (2007) How useful is the lung-to-head ratio in predicting outcome in the fetus with congenital diaphragmatic hernia? A systematic review and meta-analysis. Ultrasound Obstet Gynecol vol 30 issue 6 pp 897-906

Corbett HJ, Mann KS, Mitra I, Jesudason EC, Losty PD, Clarke RW (2007) Tracheostomy - A 10 year experience from a UK Paediatric Surgical Centre. Journal of Pediatric Surgery vol 42 pp 1251-4

Almond SL, Goyal A, Jesudason EC, Graham KE, Richard B, Selby A, Losty PD (2006) Novel use of skin substitute as rescue therapy in complicated giant exomphalos. J Pediatr Surg vol 41 pp e1-e2

Jesudason EC (2006) Small lungs and suspect smooth muscle: congenital diaphragmatic hernia and the smooth muscle hypothesis. Journal of Pediatric Surgery vol 41 pp 431-435

Connell MG, Corbett HJ, Purvis A, Losty PD and Jesudason EC (2006) Sex and Congenital Diaphragmatic Hernia. Pediatric Surgery International vol 22 pp 95-98

Gabra HO, Jesudason EC, McDowell HP, Pizer BL and Losty PD (2006) Sacrococcygeal Teratoma A 25: Year Experience in a UK Regional Centre. Journal of Pediatric Surgery vol 41 issue 9 pp 1513-6

Jesudason EC, Smith NP, Connell MG, Spiller DG, White MRH, Fernig DG and Losty PD (2006) Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth. American Journal of Physiology - Lung Cellular and Molecular Physiology vol 291 issue 4 pp L559-565

Featherstone NC, Connell MG, Fernig DG, Wray S, Burdyga TV, Losty PD, Jesudason EC (2006) Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis. American Journal of Respiratory Cell and Molecular Biology vol 35 issue 5 pp 571-578

Smith NP, Losty PD, Connell MG, Mayer U and Jesudason EC (2006) Abnormal lung development precedes oligohydramnios in a transgenic murine model of renal dysgenesis. Journal of Urology vol 175 pp 783-6

Khalil BA, Jesudason EC, Featherstone NC, Sarginson R, Kerr S, Ashworth M and Losty PD (2005) Hidden pathologies associated with (and concealed by) early gestational isolated fetal hydrothorax. Journal of Pediatric Surgery vol 40 pp E1-3

Smith NP, Jesudason EC, Featherstone NC, Corbett HJ and Losty PD (2005) Recent advances in diaphragmatic hernia. Archives of Disease in Childhood vol 90 pp 426-428

Smith NP, Jesudason EC, Goyal A, McDowell HP, Lloyd DA and Losty PD (2005) Emergent embolisation to control severe haematuria in Wilms tumour. Pediatric Surgery International vol 21 pp 313-315

Jesudason EC, Smith NP, Connell MG, Spiller DG, White MRH, Fernig DG and Losty PD (2005) Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis. American Journal of Respiratory Cell and Molecular Biology vol 32 pp 118-127

Featherstone NC, Jesudason EC, Connell MG, Fernig DG, Wray S, Losty PD and Burdyga TV (2005) Spontaneous propagating calcium waves underpin airway peristalsis in embryonic rat lung. American Journal of Respiratory Cell and Molecular Biology vol 33 pp 153-160

Baker JL, Gull S, Jesudason EC, Abernethy L and Losty PD (2003) Appendix abscess masquerading as malignancy. Archives of Disease in Childhood vol 89 pp 481-482

Almond S, Jesudason EC, Malluci C and Losty PD (2003) Occult intraspinal glass injury. Archives of Disease in Childhood vol 88 issue 801-2

Goyal A, Smith NP, Jesudason EC, Kerr S and Losty PD (2003) Octreotide for treatment of chylothorax after repair of congenital diaphragmatic hernia. Journal of Pediatric Surgery vol 38 pp E19-20

Smith NP, Jesudason EC and Losty PD (2002) Congenital diaphragmatic hernia. Paediatric Respiratory Reviews vol 3 pp 339-48

Jesudason EC (2002) Challenging embryological theories on congenital diaphragmatic hernia: Future therapeutic implications for paediatric surgery. Annals of The Royal College of Surgeons of England vol 84 pp 252-9

Jesudason EC, Connell MG, Fernig DG, Lloyd DA and Losty PD (2001) Does developing liver inhibit early lung growth in congenital diaphragmatic hernia?. Pediatric Surgery International vol 17 pp 288-293

Jesudason EC, Connell MG, Fernig DG, Lloyd DA and Losty PD (2000) In vitro effects of growth factors on lung hypoplasia in a congenital diaphragmatic hernia (CDH) model. Journal of Pediatric Surgery vol 35 pp 914-922

Jesudason EC, Connell MG, Fernig DG, Lloyd DA and Losty PD (2000) Heparin and in vitro experimental lung hypoplasia. Pediatric Surgery International vol 16 pp 247-251

Jesudason EC, Connell MG, Fernig DG, Lloyd DA and Losty PD (2000) Cell proliferation and apoptosis in experimental lung hypoplasia. Journal of Pediatric Surgery vol 35 pp 129-133

Jesudason EC, Connell MG, Fernig DG, Lloyd DA and Losty PD (2000) Early lung malformations in congenital diaphragmatic hernia. Journal of Pediatric Surgery vol 35 pp 124-127

Jesudason EC and Walker J (1999) Rectal examination in paediatric surgical practice. British Journal of Surgery vol 86 pp 376-8

Edwin Jesudason MA FRCS(Paed) MD
MRC New Investigator, Reader & Consultant Paediatric Surgeon

Tel +44 (0) 151 252 5693
Fax  +44 (0) 151 228 2024

School of Reproductive and Developmental Medicine
Division of Child Health
Royal Liverpool Children's NHS Trust
Alder Hey
Eaton Road
Liverpool
L12 2AP